This is a paid 24 week co-op position designated for an undergraduate chemistry major looking to gain laboratory experience in an industrial setting. As a member of the Discovery Chemistry team, he/she will contribute to the synthesis of heterobifunctional protein degraders. The successful candidate will be trained to independently perform multistep syntheses of complex organic compounds. The applicant is expected to possess good communication skills, an eagerness to learn, and ability to work well in teams.
Principal Duties and Responsibilities:
-Conduct multistep synthesis of heterobifunctional protein degraders with supervisor’s assistance
-Assist in designing new heterobifunctional protein degraders based on assay data
-Summarize and present findings at department meetings
-Characterize synthesized compounds by NMR and LCMS
-Conduct scientific literature searches using databases such as SciFinder
-Work together with other members of project team to accomplish scientific objectives
-Maintain an accurate and current record of experimental results in an electronic laboratory notebook
-Communicate research results to supervisor in an accurate and timely manner.
-Participate in research group and project meetings
-Maintain high standards of laboratory safety in compliance with the H3 safety manual
-Ability to start in the June/July 2022 timeframe
-Undergraduate chemistry major with a strong academic record.
-Must have completed two semesters of organic chemistry including laboratory coursework.
-Preference given to candidates who have performed independent undergraduate research as well.
-Familiar with standard analytical techniques (NMR, TLC, HPLC, mass spectroscopy)
-Strong communication skills
-Experience with ChemDraw, Powerpoint and Excel preferred
-Strong desire to learn more about medicinal chemistry and drug discovery
H3 Biomedicine requires all new hires to be fully vaccinated against COVID-19 and provide valid proof of vaccination as of their start date, to the extent permitted under applicable law. This requirement is a condition of employment at H3 Biomedicine, and it applies regardless of whether the position is located at an H3 Biomedicine site, field based or is fully remote. If you are unable to receive the vaccine for qualifying medical reasons (including pregnancy-related), or religious reasons (sincerely held religious beliefs), you will have an opportunity to request a reasonable accommodation.